Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-6172 | 6172-30724 | Italy | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, T215Y | K219H | Y188L | V21VI, V35L, E44D, V60I, K102M, S117SA, K122E, I135T, D177E, H208Y, W212C, D218E, Q278H, T286A, E297K, G335S, R356K, G359S, A360T, A371V, K385R, K390R |
| >6172-30724| codons 1-399 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALLEICTELEKDGKISKIGPENPYNTPI FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKMKKSVTVLDVGDAYFAVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLLVGSDLEIGQHRTKIEELRQYLLRCGFYTPEHKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQSQWTYQIYQEPFKNLKTGKYAKMRST HTNDVKQLTEVVQKIATESIVIWGRTPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |