Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-6132 | 6132-30624 | Italy | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F | L33F, F53L | L10V, T12I, I13V, I15V, Q18E, M36L, K45V, I62V, L63P, I72V |
| >6132-30624| codons 1-99 PQITLWQRPVVIVKVGGELKEALLDTGADDTVFEELNLPGRWKPVMIGGIGGLVKVRQYD QVPIEICGHKAVGTVLVGPTPFNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, M184V, L210W, T215Y | K219N | K103N | V108I | V35I, V118I, D121Y, K122E, I135T, S162C, D177E, T200A, D218E, A272P, K277R, T286A, I293V, E297K, K311N, G335D, K350R, R356K, G359S, A371V, T377L |
| >6132-30624| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSIPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFYTPENKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTKEAE LELAENREILNEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLRTGKYAKMRSA HTNDVKQLTEVVQKIALESIVIWGKTPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |