Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-6020 | 6020-30328 | Italy | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I50IV, I54S, V82A | L33F | L10IV, I13V, G16E, K20KT, D60E, L63S, A71V, V77I, I93L |
| >6020-30328| codons 1-99 PQITLWQRPVVTVKIEGQLTEALLDTGADDTVFEEMNLPGRWKPKMIVGVGGFSKVRQYE QISIEICGHKVIGTVLIGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M | A62V, V75I, F116Y | K103N, Y181C, G190A | K20R, S68G, V90I, K101KR, V118I, K122E, D123E, S162A, R172K, Q197K, Q207T, R211K, F214L, A272P, K277R, T286A, T296S, E297K, V317A, I329V, G333E, Q334QL, M357MR, A371AV, E399D |
| >6020-30328| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKRKDGTKWRKLIDFRELNKRTQDFWEIQLGIPHPAGLRKNKSVTVLDVGDAYYSIPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQASMTKILEPFKKQNPDIVI CQYMDDLYVASDLEIGKHRTKIEELRTHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLSKEAE LELAENREILKEPVHGAYYDPSKDLIAEVQKQELGQWTYQIYQEPFKNLKTGKYARRRGA HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWDA |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |