Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA2097 | CA7745 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV+NFV | 93 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82T, L90M | L10I, I62V, L63P, T74S, I93L |
| >CA7745| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVPIEICGHKAIGSVLVGPTPTNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, K70R, M184V | N348I | S162A, Q174R, Q207E, A272P, I293V, K311R, S322T, Q334L, G335D, R356K, K366R, A400T, E404D, D460N, L469I, L491S, S519N, Q524E, V531I, K558R |
| >CA7744| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKRNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILREPVHGVYYDPTKDLIAEIQKQGLDQWTYQIYQEPFKILKTGKYAKMRGA HTNDVRQLTEAVQKIATESIVIWGKTPKFKLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVSITDTTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKEKIYLAWVPAHK GIGGNEQVDKLVSAGIRRVL |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |