Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-4056 | 4056-30307 | Germany | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210L*W, T215Y | N348NI | K20R, K43Q, V118VI, D123E, I142IV, S162D, D177E, I178L, V179I, G196E, T200A, E203D, H208HY, R211RK, A272P, K277KR, L283I, T286TN, A288S, I293V, E297EK, Q334H, P345Q, T369TAIV, A371AITV, A376AV, T377ILM, K390R, E399ED, A400AT |
| >4056-30307| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPELII YQYVDDLYVGSDLEIEQHRAKIDELRQYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGNKSLTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTYQIYQEQFKILKTGKYARMRGA HTNDVKQLVEVVQKIVMESIVIWGKTPKFRLPIQKETWDT |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |