<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3276 3276-30716 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L210W, T215Y K219E K101E, Y181C E138K V35I, T39A, K43E, E44A, R83K, K104KR, V118I, D123E, D177E, T200A, H208Y, D218E, L228R, V245Q, A272P, K275R, I293V, Q334L, K350KR, M357T, V365I, E370Q, A376S, S379C, K390R, I393V, K395R  
>3276-30716| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEEAGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLEKKRSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
CQYMDDLYVGSDLEIGQHRAKIEELRQYLWRWGFYTPEEKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLRTGKYARTRGA
HTNDIKQLTQAVQKISTECIVIWGKTPKFRLPVQRETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54A, V82A, L90M L10F, G73S, L89V Q7QE, I15V, G16E, M36L, R41RK_KR, K55R, R57RK, Q61H, L63T, K70T, A71V, I93L  
>3276-30716| codons 1-99
PQITLWERPFVTIKVEGQLKEALLDTGADDTVLEELNLPGKWKPKLIGGIGGFARVKQYD
HITIEICGHTVISTVLVGPTPANIIGRNVMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006