<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3252 3252-30619 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N K103N F227L K20R, E44D, V106I, V118I, D123E, S163A, V179T, I195IL, G196E, E203K, H208Y, R211K, K223E, Q278E, I293IV, E297R, Q334C, R356K, G359S, A371V, A376T, T386A, K390R, E399D  
>3252-30619| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSITVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSAMTKILEPFRKQNPDITI
YQYVDDLYVGSDLELEQHRTKIKELRQYLWKWGFYTPDNKHQEEPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGTKALTEVVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGCGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEVVQKITTESIVIWGKAPKFRLPIQKETWDA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L76V, I84V, L90M L10F, L33F, L89V I13V, L19LI, M36L, I62V, L63P, I66F, A71T, T91S  
>3252-30619| codons 1-99
PQITLWQRPFVTVKIGGQIKEALLDTGADDTVFEELNLPGRWKPKIIGGIGGFIKVRQYD
QVPIEFCGHKTIGTVVVGPTPVNVIGRNVMSQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006