Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3205 | 3205-30612 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | Y188L | V35M, T39A, K43E, K101KQ, V106VI, K122E, R211K, V245K, T286A, I293V, T296S, E297K, I329L, E344D, M357T, V365VI, K385R |
| >3205-30612| codons 1-398 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSITVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLLVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLSKEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQDPFKNLKTGKYARTRGA HTNDIKQLTEAVQKIATESIVIWGRTPKFKLPIQKETW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | Q58E | L10I, L19Q, K20R, L24F, E35D, M36I, R41K, R57RK, D60X, I62V, L63P, A71V, I93L |
| >3205-30612| codons 1-99 PQITLWQRPIVTIKIGGQQREALFDTGADDTVLEDINLPGKWKPKLIGGIGGFVKVKEYX QVPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |