Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3200 | 3200-30515 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54L, L76V, I84V, L90M | L33F, G73T | L10I, I13V, G16A, E34Q, N37NHRS, R41RK, K55R, L63P, A71V, I93L | L89S |
| >3200-30515| codons 1-99 PQITLWQRPIVTVKIAGQLKEALLDTGADDTVFQEMSLPGKWKPKIIGGIGGFLRVRQYD QIPIEICGHKVITTVVVGPTPVNVIGRNSMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, M184V, L210W, T215Y | K103S | E6K, M16V, K20R, V35I, T39A, E40F, K43E, V118I, K122E, I135T, D177N, T200A, Q207D, H208Y, R211K, A272P, T286A, A288S, Q334E, A355G, M357T, A371V, A376T, A400S | E203AT |
| >3200-30515| codons 1-400 PISPIKTVPVKLKPGVDGPRVKQWPLTEEKIKALIEICAFLEEEGKISKIGPENPYNTPV FAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKSKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPNIVI YQYVDDLYVGSDLEIGQHRAKITELRDYLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKSLTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYGRTRGA HTNDVKQLTEVVQKITTESIVIWGKTPKFKLPIQKETWES |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |