<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3190 3190-30604 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L33I, K43T, F53L, L89V L10I, I13V, L19I, K20R, A22V, E35D, M36I, K55R, R57K, D60E, I62V, L63P, A71V, I72T, Q92K  
>3190-30604| codons 1-99
PQITLWQRPIVTVKIGGQIREVLLDTGADDTVIEDINLPGRWTPKLIGGIGGLVRVKQYE
QVPIEICGHKVTGTVLVGPTPANIIGRNVMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, L74V, M184V, L210W, T215Y K219E Y181C V108I K20R, V35M, T39A, K43E, E44A, K49R, K101Q, V118I, K122E, I135M, Q174K, R211T, L228H, Q242H, L283I, A288S, L325LI, I329V, R356K, M357K, G359S, A371V, K390R  
>3190-30604| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEEAGKISRIGPENPYNTPV
FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELRQHLWTWGFYTPDEKHQKEPPFHWMGYELHPDKWT
VHPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKSLTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDIIAEVQKQGQGQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006