<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3167 3167-30502 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, V82A, I84IV L24I, L33F L10I, I13V, K55R, R57K, L63P, K70Q, A71V, T74S, V77IT, L89LM, I93L  
>3167-30502| codons 1-99
PQITLWQRPIVTVKIGGQLKEALIDTGADDTIFEEMNLPGRWKPKIVGGIGGFMRVKQYD
QIPIEICGHQVIGSVLTGPTPANVIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, Q151QKLM, M184V, L210W, T215Y K219KE Y181YC   E6EK, V21I, K43N, E44D, T69TA, V111I, K122E, I142T, S162Y, G196E, T200IL, R211EK, V245M, A272P, K277R, L283I, R284RK, I293V, E297KR, G333E, R358K, G359S, A360T, Q367L, A371V, T377R G18GS, Y232YH
>3167-30502| codons 1-400
PISPIKTVPVKLKPGMDSPKIKQWPLTEEKIKALVEICTELENDGKISKIGPENPYNTPV
FAIKKKNSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYFSVPL
DEDFRKYTAFTIPSINNETPGTRYQYNVLPMGWKGSPAIFQYSMTKILEPFRKQNPDIVI
CQYVDDLYVGSDLEIEQHRLKIEELRQHLWKWGFYTPDEKHQKEPPFLWMGHELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIKGTKALTEVVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMKST
HTNDVKLLTEVVQKIARESIVIWGKTPKFKLPIQKETWEA

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006