Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3130 | 3130-30402 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, M184V, T215Y | K219Q | Y181C | A98AG | T39TA, V60I, K102KR, D121H, K122E, I135T, D177E, V179VI, T200A, R211T, D218E, L228H, A272P, K277KR, E291ED, E297A, E300Q, T386I, K390R | F77FY |
| >3130-30402| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKVVDYRELNKRTQDFWEVQLGIPHPGGLKRKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII CQYVDDLYVGSDLEIGQHRAKIEELRQHLLTWGFYTPEQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVIPLTAEAQ LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54M, V82T, L90M | F53L, L89LV | L10V, I15V, K20R, M36I, L63P, A71IV |
| >3130-30402| codons 1-99 PQITLWQRPVVTIKVGGQLREALLDTGADDTILEEINLPGRWKPKIVGGIGGLMKVRQYD QIPIEICGHKVIGTVLVGPTPTNIIGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |