Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3119 | 3119-30326 | France | 2003 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, M36I, R41K, I64L, H69K, L89M |
| >3119-30326| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, K49R, D123A, I135V, S162A, T165I, F171Y, K173T, Q174K, D177E, T200A, Q207E, V245Q, K277R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, P345PL, R356K, M357KR, G359S, A371V, I375V, K390R |
| >3119-30326| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKAFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMIKILEPYRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQELFKNLKTGKYAKRRSA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |