Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3100 | 3100-30320 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, T215Y | N348I | K101P | K11Q, E28K, K32E, E44D, V60I, V118I, I135V, T200V, E203K, Q207D, H208Y, L210Y, R211K, A272P, P294Q, S322T, R356K, G359S, K366R, A376S |
| >3100-30320| codons 1-399 PISPIETVPVQLKPGMDGPKVKQWPLTKEKIEALVEICTELEKDGKISKIGPENPYNTPI FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLPKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRVKIKELRDYLYKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIQLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYAKMRSA HTNDVRQLTEAVQKISTESIVIWGKTPKFKLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, G48V, I54M, V82A, I84V | K43T | L10I, K14R, E34Q, E35D, M36V, N37D, L63P, H69R, A71V |
| >3100-30320| codons 1-99 PQITLWQRPIVTIRIGGQLKEALLDTGADDTILQDVDLPGRWTPKMVVGIGGFMKVRQYD QIPIEICGRKVIGTVLVGPTPANVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |