<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3100 3100-30320 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I47V, G48V, I54M, V82A, I84V K43T L10I, K14R, E34Q, E35D, M36V, N37D, L63P, H69R, A71V  
>3100-30320| codons 1-99
PQITLWQRPIVTIRIGGQLKEALLDTGADDTILQDVDLPGRWTPKMVVGIGGFMKVRQYD
QIPIEICGRKVIGTVLVGPTPANVIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, T215Y N348I K101P   K11Q, E28K, K32E, E44D, V60I, V118I, I135V, T200V, E203K, Q207D, H208Y, L210Y, R211K, A272P, P294Q, S322T, R356K, G359S, K366R, A376S  
>3100-30320| codons 1-399
PISPIETVPVQLKPGMDGPKVKQWPLTKEKIEALVEICTELEKDGKISKIGPENPYNTPI
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLPKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRVKIKELRDYLYKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIQLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYAKMRSA
HTNDVRQLTEAVQKISTESIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006