Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3098 | 3098-30415 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IV, V82A, I84V | L10F, L24I, K43T, F53FL | K20R, E35D, M36I, N37D, I62V, L63A, I64V, I72V, T74S |
| >3098-30415| codons 1-99 PQITLWQRPFVTIKIGGQLREALIDTGADDTVLEDIDLPGRWTPKIIGGIGGLVKVRQYD QVAVEICGHKAVGSVLVGPTPANVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75VM, L210W, T215Y | P4PT, K43Q, V60I, V118I, K122E, D123N, T139K, S162CY, Q174N, V179I, R211K, A272P, K277R, I293V, E297A, Q334D, M357MV, T369V, T386TA, K390R |
| >3098-30415| codons 1-399 PISTIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPI FAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKNNPDIII YQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARVRGA HTNDVKQLVEAVQKIATESIVIWGKAPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |