<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3096 3096-30415 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, L74I, M184V, T215F K219Q   A98G P4PT, K20R, V35I, K43KE, T69N, V106VI, V118I, K122E, S162D, D177DN, I178IM, T200A, E203D, H208Y, R211K, F214L, L228LH, V245E, K249KQ, R284K, T286A, A288AS, I293V, D324E, M357T, D364E, V365I, A376T, K390R, E399D K64KHNQ
>3096-30415| codons 1-399
PISTIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEEEGKISKIGPENPYNTPV
FAIQKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSITVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKQNPNMVI
YQYVDDLYVGSDLEIGQHRAKIDELRQYLLKWGLFTPDQKHQKEPPFHWMGYELHPDKWT
VQPIELPEQDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGAKSLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTRGA
HTNEIKQLTEAVQKITTESIVIWGKTPKFRLPIQKETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47A, L90M L10F, Q58E I15V, E35D, M36I, I62V, L63P, A71T  
>3096-30415| codons 1-99
PQITLWQRPFVTIKVGGQLKEALLDTGADDTILEDINLPGRWKPKIAGGIGGFIKVREYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006