Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3095 | 3095-30414 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70G, L74V, Y115F, M184V, T215F | N348I | L100I, K103N | V35T, T39L, V60I, A98S, K122E, I135T, I142V, I202IV, F214L, A272P, K277KR, A288S, I293V, I329L, I341IV, M357T, K385R |
| >3095-30414| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKNSTGWRKVVDFRELNKRTQDFWEVQLGIPHPSGIKKNKSVTVLDVGDAFFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKVEELRQHLLRWGLFTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKSLTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQVYQEPFKILKTGKYARTRGA HTNDVKQLTEAVQKIATESIVIWGRTPKFKLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, V82A, L90M | L33F, K43T, G73S | L10I, I13V, G16A, I62V, L63P, A71V, I72R |
| >3095-30414| codons 1-99 PQITLWQRPIVTVKIAGQLKEALLDTGADDTVFEEMNLPGRWTPKIIGGIGGFVKVRQYD QVPIEICGHKVRSTVVVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |