<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3061 3061-30512 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54M, V82VA, L90M L10FI, G73S, L89V I13V, K20R, E35D, M36I, N37D, L63P, H69Y, K70KE, A71IV, I93L  
>3061-30512| codons 1-99
PQITLWQRPIVTVKIGGQLREALLDTGADDTILEDIDLPGRWKPKIVGGIGGFMKVRQYD
QIPIEICGYEVISTVLVGPTPANIIGRNVMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, L210W, T215Y D67G, V75T, K219D K101E, Y181C, G190A   V35I, E40F, K43E, I47IF, S68G, W88C, V118I, K122E, K166R, I195K, G196E, T200V, E203K, R211H, K223E, A272P, T286A, E297EA, V317A, I326V, I329V, Q334L, F346Y, K350R, R358K, G359S, V365I, A371V, E399D K30KR
>3061-30512| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEERIKALIEICTFLEEEGKFSKIGPENPYNTPV
FAIKKKGGTKWRKITDFRELNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
CQYVDDLYVASDLEKEQHRVKIKELRQHLWHWGFYTPDDKHQEEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTAEAE
LELAENREILKEPVHGAYYDPSKDLVAEVQKQGLGQWTYQIYQEPYKNLRTGKYARMKSA
HTNDIKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWDA

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006