Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-3041 | 3041-30304 | France | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, L210W, T215Y | K219E | G190A | F227L | V35IL, V118I, K122E, V179I, E203K, R211K, K223E, L228H, A272P, K277R, T286A, P294T, Q334D, M357S, A376S, T386I, K390R |
| >3041-30304| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVASDLEIGQHRTKIKELRQHLWKWGFYTPDEKHQEEPPLHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVITLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARSRGA HTNDVKQLTEAVQKISTESIVIWGKIPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48A, I50V, I54V, V82A | L33F | L10I, K20R, E35D, M36I, N37S, K43KQ, L63P, A71V, T74S, I93L |
| >3041-30304| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVFEDISLPGRWQPKMIAGVGGFVKVRQYD QIPIEICGHKVIGSVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |