<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3026 3026-30303 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54L, V82A, L90M L33F, F53L, G73C L10I, I13V, E34Q, N37S, K55R, L63P, I93L, C95F  
>3026-30303| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTIFQEMSLPGRWKPKIVGGIGGLLRVRQYD
QIPIEICGHKAICTVLVGPTPANIIGRNLMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, T215Y V75T, K219R   V108I, F227L K43Q, V118I, K122E, S162A, I178M, V179I, T200A, E203K, H208FY, L210Y, R211Q, K223E, L228R, Q242L, S251H, A272P, V292I, I293V, S322T, P345T, M357T, G359S, V365I, T369V, T377TI, K390R  
>3026-30303| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEQEGKISKIGPENPYNTPV
FAIKKKDSTKWRKITDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDMII
YQYMDDLYVGSDLEIGQHRAKIKELRQYLYQWGFYTPDRKHQEEPPLRWMGYELHPDKWT
VLPIVLPEKDHWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQETFKNLKTGKYARTRSA
HTNDIKQLVEAVQKIAIESIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006