<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-3019 3019-30812 France 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70GR, L74V, M184I, L210W, T215Y K219Q L100I, K103S A98G V35IT, K43N, V118I, D123E, I135T, T200A, E203K, H208Y, R211Q, D218E, K223Q, L228H, Q242H, D250E, A272P, T286A, E297K, S322T, I329IV, K350R, G359S, A371V  
>3019-30812| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELENEGKISKIGPENPYNTPV
FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKSKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYIDDLYVGSDLEIGQHRAKIKELRQYLWQWGFYTPEQKHQQEPPFHWMGYELHPDKWT
VHPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPTKDLIAEVQKQGQGQWTYQIYQEPFKNLRTGKYARMRSA
HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M L10F, L33I, Q58E, L89V T4PS, V11L, I13V, L19LV, K20I, E35D, M36I, L63P, A71V, I93L T91TCS
>3019-30812| codons 1-99
PQISLWQRPFLTVKIGGQVIEALLDTGADDTVIEDINLPGRWKPKLIGGIGGFVKVREYD
QIPIEICGHKVIGTVLVGPTPANIIGRNVMSQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006