Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-2607 | 2607-30505 | Switzerland | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, L90M | L33F, G73T, L89V | L10V, I13IV, N37H, R57K, D60E, L63P, A71V, I72E, V77I, V82I, I93L |
| >2607-30505| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVFEEMHLPGRWKPKMIGGIGGFMKVKQYE QIPIEICGHKVETTVLIGPTPINIIGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V, T215Y | A62V | K103N | V35VI, K43KN, V90I, K122E, D123DN, I135T, S162A, D177DN, L210F, R211K, L283I, T286A, V292VI, I293V, V317A, I326M, G359S, A371V, K390R |
| >2607-30505| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELENEGKISKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPNIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLFKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGAKALTEIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLMAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRSA HTNDVKQLTEVVQKIATESIVIWGKTPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |