Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-2410 | 2410-30703 | Sweden | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48GA, I54V, V82A, I84IV, L90M | L23LI, K43KT | L10I, K20R, E35D, M36I, N37S, I62IV, L63P, A71V, P79PAS, I93L |
| >2410-30703| codons 1-99 PQITLWQRPIVTIKIGGQLREAILDTGADDTVLEDISLPGRWTPKLIAGIGGFVKVRQYD QVPIEICGHKVIGTVLVGSTPANVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219R | Y188L | K20R, K43E, E44A, K101Q, V106I, V118I, V179I, R206I, R211K, I257IL, I293V, E297A, Q334E, K350KR, R358K, G359GS, A376T, T386A, K390R |
| >2410-30703| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSITVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLLVGSDLEIGQHRTKIEELIQHLWKWGFYTPDRKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDLQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLRTGKYARMKSA HTNDVKQLTEAVQKITTESIVIWGKAPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |