Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-2206 | 2206-30409 | Portugal | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, K70R, M184V, T215Y | D67G, V75I, K219Q | A98G | E6D, I31L, S68G, I178IM, V179I, Q207E, H208Y, R211K, D218E, L228H, T286A, I293IV, E312EQ, L325I, I329L, G333E, A355AT, M357T, T386I |
| >2206-30409| codons 1-399 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKLKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKGGDRWRKLIDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMII YQYVDDLYVGSDLEIGQHRTKIEELREYLLKWGFYTPEQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTEEAE LELAENREILKQPVHGVYYDPSKDIIAELQKQEQGQWTYQIYQEPFKNLKTGKYTRTRGA HTNDVKQLTEAVQKIATESIVIWGKIPKFKLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, I47IV, I54V, I84V | L10F, L33F, T74P | I13V, K45KR, I62V, L63P, I93L |
| >2206-30409| codons 1-99 PQITLWQRPFVTVKIGGQLKEALLDTGADDTIFEEMNLPGRWKPRMVGGIGGFVKVRQYD QVPIEICGHKAIGPVLVGPTPVNVIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |