Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1439 | 1439-30929 | Denmark | 2003 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | L100I, K103N | A98G | V35T, T39K, K43E, E44D, K49R, V60I, K122E, Q174K, D177E, I178M, Q207E, R211K, V245Q, D250E, A272P, L282C, L283I, R284K, T286S, I293V, E297A, G335D, P345Q, F346Y, K347KR, R356K, A360T, T377Q, S379C, K390R |
| >1439-30929| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEEDGKISRIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKCIKGSKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYRNLKTGKYAKMRGT HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76LV, V82A, L90M | L10FI | I13V, K20I, E34EK, M36I, R41K, I62V, L63P, I64IV, A71T, L89LI, I93L |
| >1439-30929| codons 1-99 PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLKEINLPGKWKPKIIGGIGGFVKVRQYD QVPVEICGHKTIGTVVVGPTPANIIGRNIMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |