Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1424 | 1424-30312 | Denmark | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | V11I, L33F, F53L, G73S | L10I, I62V, L63P, C67F, A71I, I72E, V77I, I85V, T91A |
| >1424-30312| codons 1-99 PQITLWQRPIITIKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIVGGIGGLVKVRQYD QVPIEIFGHKIESTVLIGPTPVNVVGRNLMAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | L100I, K103N | K20R, K43N, V118I, K122E, D177H, T200A, F214FL, A272P, P294T, E297R, Q334P, G359S, A360AV, A371V |
| >1424-30312| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELENEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPHIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGLYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVITLTREAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGPGQWTYQIYQEPFKNLKTGKYARMRSV HTNDVKQLTEVVQKIATESIVIWGKTPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |