<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1413 1413-30326 Denmark 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, V75M, M184V, L210W, T215Y K219KN, N348I L100I, K103N   S3SC, E6D, K20KR, V35VI, E40X, K43N, E44ED, A98S, K122E, T200A, E203EV, Q207E, L228R, A272P, K277R, E297Q, Q334L, G359S, K390KR V111VIM
>1413-30326| codons 1-399
PICPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTXLENDGKISKIGPENPYNTPV
FAIKKKDSTKWRKVMDFRELNKRTQDFWEVQLGIPHPSGIKKNKSVTVLDMGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIVELREHLWRWGFYTPDNKHQKEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTQEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKILKTGKYARMRSA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M L10F, L33F G16A, K43S, I62V, L63P, H69R, A71T, I72V, I93L, C95F  
>1413-30326| codons 1-99
PQITLWQRPFVTIKIAGQLKEALLDTGADDTVFEEMNLPGRWSPKIIGGIGGFVKVRQYD
QVPIEICGRKTVGTVLVGPTPANIIGRNLMTQLGFTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006