<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1401 1401-30716 Denmark 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA
2 NRTI+NNRTI+RTV+TPV 21

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219N K103N, Y181C, G190A E138EK E6D, K20KR, K43Q, E44D, K101Q, V118I, K122E, T200A, E203V, Q207E, H208Y, R211K, K223E, L228HR, A272P, I293V, K311R, V317A, Q334L, R356K, G359S, V365I, K390R K65K_N
>1401-30716| codons 1-399
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEQDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRAKIVELREYLWKWGFYTPDNKHQEEPPFRWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILREPVHGAYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82T, L90M V11I, F53FL, G73S L10I, I15V, K20I, M36I, R41K, K55R, Q61H, I62V, L63P, C67F, A71I, I72V, I85V, Q92K  
>1401-30716| codons 1-99
PQITLWQRPIITIKVGGQLIEALLDTGADDTVLEEINLPGKWKPKIIGGVGGLVRVRQYD
HVPIEIFGHKIVSTVLVGPTPTNIVGRNLMTKIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006