Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1202 | 1202-30702 | Belgium | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L33F, N83D | I13V, G16E, K20R, E35D, M36I, N37D, R41K, R57RK, L63N, H69K, K70R, L89I, T91V, I93L |
| >1202-30702| codons 1-99 PQITLWQRPLVTVKIEGQLREALLDTGADDTVFEDIDLPGKWKPKMIGGIGGFVKVKQYD QINIEICGKRAIGTVLVGPTPADIIGRNIMVQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E | K103KN | V35T, K43R, T69N, D121H, K122E, D123E, I142V, K173S, Q174K, D177E, T200A, Q207A, R211K, V245K, T286A, E291D, V292I, I293V, E297R, A304E, E312N, I329V, G335D, R356K, M357K, R358K, G359S, A360T, A371V, I375V, A376T, T377L, K390R, E396D |
| >1202-30702| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPV FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTREAE LELEENREILKNPVHGVYYDPSKDLIAEVQKQGQDQWTYQIYQEPFKNLKTGKYAKKKST HTNDVKQLTEVVQKVTLESIVIWGKTPKFRLPIQKDTWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |