Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1835 | 1835-30929 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82ACGS, L90M | L10F, L33F, G73S | L19I, E35D, M36L, K43S, R57K, I62V, L63P, C67W, H69R, A71V, I72M, I93L |
| >1835-30929| codons 4-99 TLWQRPFVTIKIGGQIKEALLDTGADDTVFEDLNLPGRWSPKMIGGIGGFVKVKQYDQVP IEIWGRKVMSTVLVGPTPSNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L210L*W, T215Y | K219Q | K103N, Y181C | V60VI, K66KR, I142V, S162A, Q207N, R211K, D218E, L228H, Q242H | D113N |
| >1835-30929| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKRNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGNAYFSVPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIGQHRTKIEELRNHLWKWGFYTP EQKHQKEPPFHWMGYELHPDKWTVHPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |