<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1829 1829-30924 Mexico 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, T215F D67T, K219E Y181C V108I, V179E T69N, K103R, K122E, D123E, I135IM, S162C, I202V, R211K, L228HR H235HR
>1829-30924| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFAIKKKTSNRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKRKSVTILDVGDAYFSVPLDEEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKQNPDIEICQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFFTP
DEKHQKEPPFRWMGYELRPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M G73S L10I, I62V, L63P, A71V, V77I  
>1829-30924| codons 4-99
TLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYDQVP
IEICGHKVISTVLIGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006