Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1829 | 1829-30924 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | G73S | L10I, I62V, L63P, A71V, V77I |
| >1829-30924| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYDQVP IEICGHKVISTVLIGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67T, K219E | Y181C | V108I, V179E | T69N, K103R, K122E, D123E, I135IM, S162C, I202V, R211K, L228HR, H235HR |
| >1829-30924| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKTSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKRKSVTILDVGDAYFSVPLDEEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIEICQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFFTP DEKHQKEPPFRWMGYELRPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |