Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1833 | 1833-30924 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54IV, L76LV, V82VA | L10I, G16GE, K20KR, M36I, N37ND, R41RK, L63T, I72IV, L89LM |
| >1833-30924| codons 4-99 TLWQRPIVTIKIEGQLREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVKVRQYDQIT IEICGHKAVGTVVVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74LI, M184V, L210W, T215Y | K219KN | Y181YC, G190GA | K43KE, E44EA, V118I, D121DH, K122E, D123E, Q197K, T200TA, Q207A, R211K |
| >1833-30924| codons 38-247 CTELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLHEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGKHRAKIEELRAHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |