Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1816 | 1816-30929 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Q151M, M184I | A62V, V75I, F77L, F116Y | K101E, Y181C, G190A | S68G, D123E, I142V, S162C, Q174QR, I178L, L228R, V245E |
| >1816-30929| codons 38-246 CTEMEKEGKISKIGPENPYNTPVFVIKRKDGTRWRKLIDLRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYYSVPLDKEFRKYTAFTIPSINNETPGVRYQYNVLPMGWKGSP AIFQCSMTKILEPFRKRNPDLVICQYIDDLYVASDLEIGQHRTKIEELRQHLLRWGFTTP DKKHQKEPPFRWMGYELHPDKWTVQPIEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | L10F, V11I, Q58E, G73S | I13V, L19Q, K20I, M36I, R41K, K55KR, L63P, H69R, A71I, I72IM, I93L |
| >1816-30929| codons 4-99 TLWQRPFITVKIGGQQIEALLDTGADDTVLEEINLPGKWKPKIVGGIGGFVRVREYDQIP IEICGRKIMSTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |