Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1813 | 1813-30927 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, Q151QKLM, T215F | K219EQ | T69TN, K102Q, K103R, V118I, K122E, D123E, I202V, H208HY, F214L |
| >1813-30927| codons 38-246 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKQRKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKVEELRQYLLRWGLFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84IV, L90M | F53FL | L10I, E35D, M36I, K43KE, D60E, I62V, L63P, A71V | L89LP |
| >1813-30927| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWEPKMIGGIGGLVKVRQYEQVP IEICGHKVIGTVLVGPTPANVIGRNPMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |