Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1828 | 1828-30929 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | Y188L | T39TS, V60VI, T69TN, L109I, K122P, I142IV, D177E, V179I, I202IV, R211K, D218E, V245R |
| >1828-30929| codons 38-247 CSEMEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVIDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIIIYQYMDDLLVGSDLEIGQHRTKVEELRQHLLKWGFFTP EQKHQKEPPFLWMGYELHPDKWTVQPIRLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15IV, E35D, M36I, N37E, R57RK, L63P, K70R |
| >1828-30929| codons 4-99 TLWQRPLVTIKVGGQLKEALLDTGADDTVLEDIELPGRWKPKMIGGIGGFIKVKQYDQIP IEICGHRAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |