<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1805 1805-30923 Mexico 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L210W, T215CY K219DE L100I, Y181YC, G190GA A98G, V179D T39A, E44D, K102KQ, K103KR, V106VI, K122E, I135T, I142V, D177E, H208Y, R211K, L228H  
>1805-30923| codons 38-247
CAELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
GGIKQRKSITVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIDICQYMDDLYVASDLEIGQHRTKIEELRQYLWKWGFYTP
DEKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M F53L I15V, K20R, M36I, N37D, R57K, D60E, L63P, A71V, I72IV L10DV
>1805-30923| codons 4-99
TLWQRPVVTIKVGGQLREALLDTGADDTVLEEIDLPGRWKPKMIGGIGGLIKVKQYEQIP
IEICGHKVVGTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006