Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1817 | 1817-30924 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F, I84V, L90M | Q58E, G73S, L89V | L10I, I13IV, I15V, L19V, K20M, M36L, L38W, I62V, L63P, A71V, I72IM |
| >1817-30924| codons 4-99 TLWQRPIVTVKVGGQVMEALLDTGADDTVLEELNWPGRWKPKMIGGIGGFVKVREYDQVP IEICGHKVMSTVLVGPTPFNVIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W | T215D | Y181C, G190A | A98G, K101N | T39A, K43Q, E44D, V106VI, V118I, K122E, I135T, Q174K, E203EK, Q207E, H208Y, R211K |
| >1817-30924| codons 38-247 CAELEQDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLNKKKSITVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKKNPDIVICQYMDDLYVASDLEIGQHRTKIKELREYLWKWGFDTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |