<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1804 1804-30923 Mexico 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y K219N     T39A, K43Q, E44D, V60I, V118I, K122E, D123E, I135T, V179I, G196E, I202V, E203K, Q207E, H208Y, R211K, K223E, L228H  
>1804-30923| codons 38-247
CAELEQDGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIEQHRTKVKELREYLWKWGFYTP
DNKHQEEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54M, V82A, L90M L33F, K43KT L10I, I13IV, I15V, L19Q, K20R, E34EA, E35D, M36I, N37NK, R57K, I62V, L63P, A71IV, T74S, I93L  
>1804-30923| codons 4-99
TLWQRPIVTVKVGGQQREALLDTGADDTVFADIKLPGRWTPKMIGGIGGFMKVKQYDQVP
IEICGHKVIGSVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006