Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1804 | 1804-30923 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82A, L90M | L33F, K43KT | L10I, I13IV, I15V, L19Q, K20R, E34EA, E35D, M36I, N37NK, R57K, I62V, L63P, A71IV, T74S, I93L |
| >1804-30923| codons 4-99 TLWQRPIVTVKVGGQQREALLDTGADDTVFADIKLPGRWTPKMIGGIGGFMKVKQYDQVP IEICGHKVIGSVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219N | T39A, K43Q, E44D, V60I, V118I, K122E, D123E, I135T, V179I, G196E, I202V, E203K, Q207E, H208Y, R211K, K223E, L228H |
| >1804-30923| codons 38-247 CAELEQDGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIEQHRTKVKELREYLWKWGFYTP DNKHQEEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |