Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1803 | 1803-30923 | Mexico | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L74LV, M184V, L210LW, T215Y | K103N | K238T | T39TA, K43KN, K64KN, K82KR, A98AS, V118VI, K122E, I135T, I142T, I178IM, T200A, R211X, V245E | N137ND |
| >1803-30923| codons 38-247 CAELENEGKISKIGPENPYNTPVFAINKKNSTKWRKVVDFRELNRRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNDETPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLWXWGFYTP DKKHQKEPPFLWMGYELHPDTWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19Q, R41RK, R57RK, A71V, I72T, I93L |
| >1803-30923| codons 4-99 TLWQRPLVTIKIGGQQKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVKQYDQIL IEICGHKVTGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |