<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1803 1803-30923 Mexico 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74LV, M184V, L210LW, T215Y   K103N K238T T39TA, K43KN, K64KN, K82KR, A98AS, V118VI, K122E, I135T, I142T, I178IM, T200A, R211X, V245E N137ND
>1803-30923| codons 38-247
CAELENEGKISKIGPENPYNTPVFAINKKNSTKWRKVVDFRELNRRTQDFWEVQLGIPHP
SGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNDETPGTRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLWXWGFYTP
DKKHQKEPPFLWMGYELHPDTWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19Q, R41RK, R57RK, A71V, I72T, I93L  
>1803-30923| codons 4-99
TLWQRPLVTIKIGGQQKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVKQYDQIL
IEICGHKVTGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006