Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1130 | 1130-30915 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82S | L33F, K43T | L10I, N37D, I62V, L63P, A71T, I72E, V77I, I93L |
| >1130-30915| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMDLPGRWTPKMIVGIGGFVKVRQYDQVP IEICGHKTEGTVLIGPTPSNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | T39A, K102E, D123E, I142T, I178IM, V179VIM, V189VI, Q207E, R211K, L228H, D237DN |
| >1130-30915| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKEKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMMIYQYMDDLYIGSDLEIGQHRTKIEELREHLWKWGFYTP DKKHQKEPPFHWMGYELHPNKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |