Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1122 | 1122-30729 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74I, T215F | K219Q | G190Q | A98G, V179D | V118I, K122E, I135T, Q197L, R211S, F214L, V245E | D113DY, R143RG |
| >1122-30729| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGYAYFSIPLDEDFRKYTAFTIPSTNNETPGIGYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIDIYQYMDDLYVQSDLEIGLHRTKIEELRQHLLSWGLFTP DQKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, V82A | L10I, K20KR, E35D, M36I, N37D, R57K, I62V, L63P, C67CS, A71T, I72IT |
| >1122-30729| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVKQYDQVP IEISGHKTTGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |