Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1101 | 1101-30630 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, L74V, L210W | T215ACGS | L100I, K103N | D121H, K122E, I135T, I142V, T165I, Q174QH, I202V, E203Q, Q207DH, H208HY, R211K |
| >1101-30630| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMIKILEPFRKHNPDIVIYQYMDDLYVGSDLEIGQHRTKVQELRHYLWKWGFSTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | G73T | L10I, L19I, K20I, E35D, M36I, P39Q, L63P, I64V, I72V, V77VI |
| >1101-30630| codons 4-99 TLWQRPIVTIKIGGQIIEALLDTGADDTVLEDINLQGRWKPKIIGGIGGFIKVRQYDQIP VEICGHKAVTTVLIGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |