Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1026 | 1026-30623 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82C, I84V | L24I, Q58E, T74P | L10I, I15V, L19T, K55R, L63P, A71AV, I72IR, V77I |
| >1026-30623| codons 4-99 TLWQRPIVTIKVGGQTKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVREYDQIP IEICGHKVRGPVLIGPTPCNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215V, K219Q | K103KNRS | V60I, T69TN, I135T, R172RK, I195T, G196GE, Q197P, T200A, F214L |
| >1026-30623| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKSKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLETEPHRAKIEELRQHLLRWGLVTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |