Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1151 | 1151-30929 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70G, V75T | A62V | V106A | F227L | I135L, E138G, F171FL, T200A |
| >1151-30929| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDSTGWRKLTDFRELNKRTQDFWEVQLGIPHP AGLKKKKSATVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNGTPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPLRKQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTP DKKHQKEPPLLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I93L |
| >1151-30929| codons 4-99 TLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNIP IEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |