<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-1151 1151-30929 Argentina 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, I93L  
>1151-30929| codons 4-99
TLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNIP
IEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70G, V75T A62V V106A F227L I135L, E138G, F171FL, T200A  
>1151-30929| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIKKKDSTGWRKLTDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSATVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNGTPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPLRKQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTP
DKKHQKEPPLLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006