Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1028 | 1028-30623 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L74LV, M184V, L210LW, T215Y | K103N | R83K, A98S, V118VI, K122KE, D123E, I135T, S162Y, G196GE, R211RK |
| >1028-30623| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKKTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54L, L76V, I84V, L90M | L33F | L10I, I13V, G16A, K20T, N37E, K55R, I62IV, L63P, I66IV, A71V, I93L |
| >1028-30623| codons 4-99 TLWQRPIVTVKIAGQLTEALLDTGADDTVFEEMELPGRWKPKIIGGIGGFLRVRQYDQVP IEVCGHKVIGTVVVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |