Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-1029 | 1029-30623 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46ML, I84IV, L90LM | G73GA, N88D | I62V, L63P, K70KR, I72V, V77I, I93L |
| >1029-30623| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKLIGGIGGFIKVRQYDQVP IEICGHRAVATVLIGPTPVNVIGRDLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | I50IM, V106VI, K122KE, D123DE, T200I, Q207A, R211K, F214L, V245VM |
| >1029-30623| codons 38-247 CTEMEKEGKISKMGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSITVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRIKIEELRAHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |